Publications
all bioinformatics neuroinformatics synthetic biology systems biology complex systems machine intelligence knowledge management
2024
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An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repressionin eLife, 12, October 2024
@ARTICLE{Siachisumo2024, title = {An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression}, author = {Siachisumo, Chileleko and Luzzi, Sara and Aldalaqan, Saad and Hysenaj, Gerald and Dalgliesh, Caroline and Cheung, Kathleen and Gazzara, Matthew R and Yonchev, Ivaylo D and James, Katherine and Kheirollahi Chadegani, Mahsa and Ehrmann, Ingrid E and Smith, Graham R and Cockell, Simon J and Munkley, Jennifer and Wilson, Stuart A and Barash, Yoseph and Elliott, David J}, year = 2024, doi = {10.7554/eLife.89705.3}, month = oct, journal = {eLife}, volume = {12}
2023
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Influence of the Antigen Pattern Vector on the Dynamics in a Perceptron-Based Artificial Immune - Tumour- Ecosystem During and After Radiation Therapyin Artificial Life and Evolutionary Computation. WIVACE 2021, p.195-206, Cham., January 2023
@INPROCEEDINGS{Scheidegger2023, title = {Influence of the Antigen Pattern Vector on the Dynamics in a Perceptron-Based Artificial Immune - Tumour- Ecosystem During and After Radiation Therapy}, author = {Scheidegger, Stephan and Mingo Barba, Sergio and Fellermann, Harold and Gaipl , Udo}, year = 2023, month = jan, booktitle = {Artificial Life and Evolutionary Computation. WIVACE 2021}, pages = {195--206}, address = {Cham.} }
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A knowledge integration strategy for the selection of a robust multi-stress biomarkers panel for Bacillus subtilisin Synthetic and Systems Biotechnology, 8(1):97-106, March 2023
@ARTICLE{Huang2023, title = {A knowledge integration strategy for the selection of a robust multi-stress biomarkers panel for Bacillus subtilis}, author = {Huang, Yiming and Sinha, Nishant and Wipat, Anil and Bacardit, Jaume}, year = 2023, doi = {10.1016/j.synbio.2022.12.001}, month = mar, journal = {Synthetic and Systems Biotechnology}, volume = {8}, number = {1}, pages = {97--106} }
2022
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OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Productionin ACS Synthetic Biology, 11(4):1531-1541, April 2022
@ARTICLE{Jiang2022, title = {OptDesign: Identifying Optimum Design Strategies in Strain Engineering for Biochemical Production}, author = {Jiang, Shouyong and Otero-Muras, Irene and Banga, Julio R. and Wang, Yong and Kaiser, Marcus and Krasnogor, Natalio}, year = 2022, doi = {10.1021/acssynbio.1c00610}, month = apr, journal = {ACS Synthetic Biology}, volume = {11}, number = {4}, pages = {1531--1541} }
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Computational Network Inference for Bacterial Interactomicsin mSystems, 7(2), April 2022
@ARTICLE{James2022, title = {Computational Network Inference for Bacterial Interactomics}, author = {James, Katherine and Muñoz-Muñoz, Jose}, year = 2022, doi = {10.1128/msystems.01456-21}, month = apr, journal = {mSystems}, volume = {7}, number = {2}
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Editorial: The 2019 Conference on Artificial Life Special Issuein Artificial Life, 28(2):171-172, June 2022
@ARTICLE{Fellermann2022, title = {Editorial: The 2019 Conference on Artificial Life Special Issue}, author = {Fellermann, Harold and Füchslin, Rudolf M.}, year = 2022, doi = {10.1162/artl_e_00380}, month = jun, journal = {Artificial Life}, volume = {28}, number = {2}, pages = {171--172} }
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Expanding interactome analyses beyond model eukaryotesin Briefings in Functional Genomics, 21(4):243-269, July 2022
@ARTICLE{James2022b, title = {Expanding interactome analyses beyond model eukaryotes}, author = {James, Katherine and Wipat, Anil and Cockell, Simon J}, year = 2022, doi = {10.1093/bfgp/elac007}, month = jul, journal = {Briefings in Functional Genomics}, volume = {21}, number = {4}, pages = {243--269} }
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Individualised computational modelling of immune mediated disease onset, flare and clearance in psoriasisin PLOS Computational Biology, 18(9):e1010267, September 2022
@ARTICLE{Shmarov2022, title = {Individualised computational modelling of immune mediated disease onset, flare and clearance in psoriasis}, author = {Shmarov, Fedor and Smith, Graham R. and Weatherhead, Sophie C. and Reynolds, Nick J. and Zuliani, Paolo}, year = 2022, doi = {10.1371/journal.pcbi.1010267}, month = sep, journal = {PLOS Computational Biology}, volume = {18}, number = {9}, pages = {e1010267} }
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Coupled CFD‐DEM modeling to predict how EPS affects bacterial biofilm deformation, recovery and detachment under flow conditionsin Biotechnology and Bioengineering, 119(9):2551-2563, September 2022
@ARTICLE{Xia2022, title = {Coupled CFD‐DEM modeling to predict how EPS affects bacterial biofilm deformation, recovery and detachment under flow conditions}, author = {Xia, Yuqing and Jayathilake, Pahala G. and Li, Bowen and Zuliani, Paolo and Deehan, David and Longyear, Jennifer and Stoodley, Paul and Chen, Jinju}, year = 2022, doi = {10.1002/bit.28146}, month = sep, journal = {Biotechnology and Bioengineering}, volume = {119}, number = {9}, pages = {2551--2563} }
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Integration of probabilistic functional networks without an external Gold Standardin BMC Bioinformatics, 23(1), December 2022
@ARTICLE{James2022a, title = {Integration of probabilistic functional networks without an external Gold Standard}, author = {James, Katherine and Alsobhe, Aoesha and Cockell, Simon J and Wipat, Anil and Pocock, Matthew}, year = 2022, doi = {10.1186/s12859-022-04834-4}, month = dec, journal = {BMC Bioinformatics}, volume = {23}, number = {1}
2021
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CFD–DEM modelling of biofilm streamer oscillations and their cohesive failure in fluid flowin Biotechnology and Bioengineering, 118(2):918-929, February 2021
@ARTICLE{Xia2021, title = {CFD–DEM modelling of biofilm streamer oscillations and their cohesive failure in fluid flow}, author = {Xia, Yuqing and Jayathilake, Pahala G. and Li, Bowen and Zuliani, Paolo and Chen, Jinju}, year = 2021, doi = {10.1002/bit.27619}, month = feb, journal = {Biotechnology and Bioengineering}, volume = {118}, number = {2}, pages = {918--929} }
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Toward Full-Stack In Silico Synthetic Biology: Integrating Model Specification, Simulation, Verification, and Biological Compilationin ACS Synthetic Biology, 10(8):1931-1945, August 2021
@ARTICLE{Konur2021, title = {Toward Full-Stack In Silico Synthetic Biology: Integrating Model Specification, Simulation, Verification, and Biological Compilation}, author = {Konur, Savas and Mierla, Laurentiu and Fellermann, Harold and Ladroue, Christophe and Brown, Bradley and Wipat, Anil and Twycross, Jamie and Dun, Boyang Peter and Kalvala, Sara and Gheorghe, Marian and Krasnogor, Natalio}, year = 2021, doi = {10.1021/acssynbio.1c00143}, month = aug, journal = {ACS Synthetic Biology}, volume = {10}, number = {8}, pages = {1931--1945} }
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Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralisin Applied and Environmental Microbiology, 87(22), October 2021
@ARTICLE{Choo2021, title = {Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralis}, author = {Choo, Siew Woh and Mohammed, Waleed K. and Mutha, Naresh V. R. and Rostami, Nadia and Ahmed, Halah and Krasnogor, Natalio and Tan, Geok Yuan Annie and Jakubovics, Nicholas S.}, year = 2021, doi = {10.1128/AEM.01558-21}, month = oct, journal = {Applied and Environmental Microbiology}, volume = {87}, number = {22}
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The use of psoriasis biomarkers, including trajectory of clinical response, to predict clearance and remission duration to UVB phototherapyin Journal of the European Academy of Dermatology and Venereology, 35(11):2250-2258, November 2021
@ARTICLE{Watson2021, title = {The use of psoriasis biomarkers, including trajectory of clinical response, to predict clearance and remission duration to UVB phototherapy}, author = {Watson, N. and Wilson, N. and Shmarov, F. and Zuliani, P. and Reynolds, N. J. and Weatherhead, S. C.}, year = 2021, doi = {10.1111/jdv.17519}, month = nov, journal = {Journal of the European Academy of Dermatology and Venereology}, volume = {35}, number = {11}, pages = {2250--2258} }
2020
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NIHBA: a network interdiction approach for metabolic engineering designin Bioinformatics, 36(11):3482-3492, June 2020
@ARTICLE{Jiang2020, title = {NIHBA: a network interdiction approach for metabolic engineering design}, author = {Jiang, Shouyong and Wang, Yong and Kaiser, Marcus and Krasnogor, Natalio}, year = 2020, doi = {10.1093/bioinformatics/btaa163}, month = jun, journal = {Bioinformatics}, volume = {36}, number = {11}, pages = {3482--3492} }
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Probabilistic Reachability for Uncertain Stochastic Hybrid Systems via Gaussian Processesin 2020 18th ACM-IEEE International Conference on Formal Methods and Models for System Design (MEMOCODE), p.1-11, Jaipur, India, December 2020
@INPROCEEDINGS{Vasileva2020, title = {Probabilistic Reachability for Uncertain Stochastic Hybrid Systems via Gaussian Processes}, author = {Vasileva, Mariia and Shmarov, Fedor and Zuliani, Paolo}, year = 2020, doi = {10.1109/MEMOCODE51338.2020.9315182}, month = dec, booktitle = {2020 18th ACM-IEEE International Conference on Formal Methods and Models for System Design (MEMOCODE)}, pages = {1--11}, address = {Jaipur, India} }
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Automated Synthesis of Safe Digital Controllers for Sampled-Data Stochastic Nonlinear Systemsin IEEE Access, 8:180825-180843, 2020
@ARTICLE{Shmarov2020, title = {Automated Synthesis of Safe Digital Controllers for Sampled-Data Stochastic Nonlinear Systems}, author = {Shmarov, Fedor and Soudjani, Sadegh and Paoletti, Nicola and Bartocci, Ezio and Lin, Shan and Smolka, Scott A. and Zuliani, Paolo}, year = 2020, doi = {10.1109/ACCESS.2020.3028476}, journal = {IEEE Access}, volume = {8}, pages = {180825--180843} }
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Modelling Artificial Immune – Tumor Ecosystem Interaction During Radiation Therapy Using a Perceptron – Based Antigen Pattern Recognitionin The 2020 Conference on Artificial Life, p.541-548, Online, 2020
@INPROCEEDINGS{Scheidegger2020, title = {Modelling Artificial Immune – Tumor Ecosystem Interaction During Radiation Therapy Using a Perceptron – Based Antigen Pattern Recognition}, author = {Scheidegger, Stephan and Mikos, Alexander and Fellermann, Harold}, year = 2020, doi = {10.1162/isal_a_00271}, booktitle = {The 2020 Conference on Artificial Life}, pages = {541--548}, address = {Online} }
2019
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Bayesian emulation and calibration of an individual-based model of microbial communitiesin Journal of Computational Science, 30(C):194-208, January 2019
@ARTICLE{Oyebamiji2019, title = {Bayesian emulation and calibration of an individual-based model of microbial communities}, author = {Oyebamiji, O. K. and Wilkinson, D. J. and Li, B. and Jayathilake, P. G. and Zuliani, P. and Curtis, T. P.}, year = 2019, doi = {10.1016/j.jocs.2018.12.007}, month = jan, journal = {Journal of Computational Science}, volume = {30}, number = {C}, pages = {194--208} }
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Modelling bacterial twitching in fluid flows: a CFD-DEM approachin Scientific Reports, 9(1), October 2019
@ARTICLE{Jayathilake2019, title = {Modelling bacterial twitching in fluid flows: a CFD-DEM approach}, author = {Jayathilake, Pahala Gedara and Li, Bowen and Zuliani, Paolo and Curtis, Tom and Chen, Jinju}, year = 2019, doi = {10.1038/s41598-019-51101-3}, month = oct, journal = {Scientific Reports}, volume = {9}, number = {1}
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Easybiotics: a GUI for 3D physical modelling of multi-species bacterial populationsin Bioinformatics, 35(19):3859-3860, October 2019
@ARTICLE{Naylor2019, title = {Easybiotics: a GUI for 3D physical modelling of multi-species bacterial populations}, author = {Naylor, Jonathan and Fellermann, Harold and Krasnogor, Natalio}, year = 2019, doi = {10.1093/bioinformatics/btz131}, month = oct, journal = {Bioinformatics}, volume = {35}, number = {19}, pages = {3859--3860} }
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Pathways to cellular supremacy in biocomputingin Nature Communications, 10(1), November 2019
@ARTICLE{Grozinger2019, title = {Pathways to cellular supremacy in biocomputing}, author = {Grozinger, Lewis and Amos, Martyn and Gorochowski, Thomas E. and Carbonell, Pablo and Oyarzún, Diego A. and Stoof, Ruud and Fellermann, Harold and Zuliani, Paolo and Tas, Huseyin and Goñi-Moreno, Angel}, year = 2019, doi = {10.1038/s41467-019-13232-z}, month = nov, journal = {Nature Communications}, volume = {10}, number = {1}
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Optimizing Radiation Therapy Treatments by Exploring Tumour Ecosystem Dynamics in – silicoin The 2019 Conference on Artificial Life, p.236-242, Newcastle, United Kingdom, 2019
@INPROCEEDINGS{Scheidegger2019, title = {Optimizing Radiation Therapy Treatments by Exploring Tumour Ecosystem Dynamics in – silico}, author = {Scheidegger, Stephan and Fellermann, Harold}, year = 2019, doi = {10.1162/isal_a_00167}, booktitle = {The 2019 Conference on Artificial Life}, pages = {236--242}, address = {Newcastle, United Kingdom} }
2018
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A Bayesian approach to modelling the impact of hydrodynamic shear stress on biofilm deformationin PLOS ONE, 13(4):e0195484, April 2018
@ARTICLE{Oyebamiji2018, title = {A Bayesian approach to modelling the impact of hydrodynamic shear stress on biofilm deformation}, author = {Oyebamiji, Oluwole K. and Wilkinson, Darren J. and Jayathilake, Pahala Gedara and Rushton, Steve P. and Bridgens, Ben and Li, Bowen and Zuliani, Paolo}, year = 2018, doi = {10.1371/journal.pone.0195484}, month = apr, journal = {PLOS ONE}, volume = {13}, number = {4}, pages = {e0195484} }
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The fittest, the common, and the dullest: Selection dynamics of exact autocatalytic replicatorsin The 2018 Conference on Artificial Life, p.370-371, Tokyo, Japan, 2018
@INPROCEEDINGS{Shirt-Ediss2018, title = {The fittest, the common, and the dullest: Selection dynamics of exact autocatalytic replicators}, author = {Shirt-Ediss, Ben and Krasnogor, Natalio and Fellermann, Harold}, year = 2018, doi = {10.1162/isal_a_00070}, booktitle = {The 2018 Conference on Artificial Life}, pages = {370--371}, address = {Tokyo, Japan} }
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Stochastic Rate Parameter Inference Using the Cross-Entropy Methodin Computational Methods in Systems Biology, Lecture Notes in Computer Science 11095, p.146-164, 2018
@INCOLLECTION{Revell2018, title = {Stochastic Rate Parameter Inference Using the Cross-Entropy Method}, author = {Revell, Jeremy and Zuliani, Paolo}, year = 2018, doi = {10.1007/978-3-319-99429-1_9}, booktitle = {Computational Methods in Systems Biology}, publisher = {Springer International Publishing}, volume = {11095}, series = {Lecture Notes in Computer Science}, pages = {146--164} }
2017
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Simbiotics: A Multiscale Integrative Platform for 3D Modeling of Bacterial Populationsin ACS Synthetic Biology, 6(7):1194-1210, July 2017
@ARTICLE{Naylor2017, title = {Simbiotics: A Multiscale Integrative Platform for 3D Modeling of Bacterial Populations}, author = {Naylor, Jonathan and Fellermann, Harold and Ding, Yuchun and Mohammed, Waleed K. and Jakubovics, Nicholas S. and Mukherjee, Joy and Biggs, Catherine A. and Wright, Phillip C. and Krasnogor, Natalio}, year = 2017, doi = {10.1021/acssynbio.6b00315}, month = jul, journal = {ACS Synthetic Biology}, volume = {6}, number = {7}, pages = {1194--1210} }
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A mechanistic Individual-based Model of microbial communitiesin PLOS ONE, 12(8):e0181965, August 2017
@ARTICLE{Jayathilake2017, title = {A mechanistic Individual-based Model of microbial communities}, author = {Jayathilake, Pahala Gedara and Gupta, Prashant and Li, Bowen and Madsen, Curtis and Oyebamiji, Oluwole and González-Cabaleiro, Rebeca and Rushton, Steve and Bridgens, Ben and Swailes, David and Allen, Ben and McGough, A. Stephen and Zuliani, Paolo and Ofiteru, Irina Dana and Wilkinson, Darren and Chen, Jinju and Curtis, Tom}, year = 2017, doi = {10.1371/journal.pone.0181965}, month = aug, journal = {PLOS ONE}, volume = {12}, number = {8}, pages = {e0181965} }
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Sequence selection by dynamical symmetry breaking in an autocatalytic binary polymer modelin Physical Review E, 96(6), December 2017
@ARTICLE{Fellermann2017, title = {Sequence selection by dynamical symmetry breaking in an autocatalytic binary polymer model}, author = {Fellermann, Harold and Tanaka, Shinpei and Rasmussen, Steen}, year = 2017, doi = {10.1103/PhysRevE.96.062407}, month = dec, journal = {Physical Review E}, volume = {96}, number = {6}
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SMT-based Synthesis of Safe and Robust PID Controllers for Stochastic Hybrid Systemsin Hardware and Software: Verification and Testing, Lecture Notes in Computer Science 10629, p.131-146, 2017
@INCOLLECTION{Shmarov2017, title = {SMT-based Synthesis of Safe and Robust PID Controllers for Stochastic Hybrid Systems}, author = {Shmarov, Fedor and Paoletti, Nicola and Bartocci, Ezio and Lin, Shan and Smolka, Scott A. and Zuliani, Paolo}, year = 2017, doi = {10.1007/978-3-319-70389-3_9}, booktitle = {Hardware and Software: Verification and Testing}, publisher = {Springer International Publishing}, volume = {10629}, series = {Lecture Notes in Computer Science}, pages = {131--146} }
2016
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Annotation of rule-based models with formal semantics to enable creation, analysis, reuse and visualizationin Bioinformatics, 32(6):908-917, March 2016
@ARTICLE{Misirli2015, title = {Annotation of rule-based models with formal semantics to enable creation, analysis, reuse and visualization}, author = {Misirli, Goksel and Cavaliere, Matteo and Waites, William and Pocock, Matthew and Madsen, Curtis and Gilfellon, Owen and Honorato-Zimmer, Ricardo and Zuliani, Paolo and Danos, Vincent and Wipat, Anil}, year = 2016, doi = {10.1093/bioinformatics/btv660}, month = mar, journal = {Bioinformatics}, volume = {32}, number = {6}, pages = {908--917} }
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Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 1in Frontiers of Chemical Science and Engineering, 10(2):186-195, June 2016
@ARTICLE{Best2015, title = {Transformer2 proteins protect breast cancer cells from accumulating replication stress by ensuring productive splicing of checkpoint kinase 1}, author = {Best, Andrew and James, Katherine and Hysenaj, Gerald and Tyson-Capper, Alison and Elliott, David J.}, year = 2016, doi = {10.1007/s11705-015-1540-4}, month = jun, journal = {Frontiers of Chemical Science and Engineering}, volume = {10}, number = {2}, pages = {186--195} }
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Functional networks inference from rule-based machine learning modelsin BioData Mining, 9(1), December 2016
@ARTICLE{Lazzarini2016, title = {Functional networks inference from rule-based machine learning models}, author = {Lazzarini, Nicola and Widera, Paweł and Williamson, Stuart and Heer, Rakesh and Krasnogor, Natalio and Bacardit, Jaume}, year = 2016, doi = {10.1186/s13040-016-0106-4}, month = dec, journal = {BioData Mining}, volume = {9}, number = {1}
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Probabilistic Hybrid Systems Verification via SMT and Monte Carlo Techniquesin Hardware and Software: Verification and Testing, Lecture Notes in Computer Science 10028, p.152-168, 2016
@INCOLLECTION{Shmarov2016, title = {Probabilistic Hybrid Systems Verification via SMT and Monte Carlo Techniques}, author = {Shmarov, Fedor and Zuliani, Paolo}, year = 2016, doi = {10.1007/978-3-319-49052-6_10}, booktitle = {Hardware and Software: Verification and Testing}, publisher = {Springer International Publishing}, volume = {10028}, series = {Lecture Notes in Computer Science}, pages = {152--168} }
2015
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Meta-Stochastic Simulation of Biochemical Models for Systems and Synthetic Biologyin ACS Synthetic Biology, 4(1):39-47, January 2015
@ARTICLE{Sanassy2014, title = {Meta-Stochastic Simulation of Biochemical Models for Systems and Synthetic Biology}, author = {Sanassy, Daven and Widera, Paweł and Krasnogor, Natalio}, year = 2015, doi = {10.1021/sb5001406}, month = jan, journal = {ACS Synthetic Biology}, volume = {4}, number = {1}, pages = {39--47} }
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Qualitative and Quantitative Analysis of Systems and Synthetic Biology Constructs using P Systemsin ACS Synthetic Biology, 4(1):83-92, January 2015
@ARTICLE{Konur2015, title = {Qualitative and Quantitative Analysis of Systems and Synthetic Biology Constructs using P Systems}, author = {Konur, Savas and Gheorghe, Marian and Dragomir, Ciprian and Mierla, Laurentiu and Ipate, Florentin and Krasnogor, Natalio}, year = 2015, doi = {10.1021/sb500134w}, month = jan, journal = {ACS Synthetic Biology}, volume = {4}, number = {1}, pages = {83--92} }
2014
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JEPETTO: a Cytoscape plugin for gene set enrichment and topological analysis based on interaction networksin Bioinformatics, 30(7):1029-1030, April 2014
@ARTICLE{Winterhalter2013, title = {JEPETTO: a Cytoscape plugin for gene set enrichment and topological analysis based on interaction networks}, author = {Winterhalter, C. and Widera, P. and Krasnogor, N.}, year = 2014, doi = {10.1093/bioinformatics/btt732}, month = apr, journal = {Bioinformatics}, volume = {30}, number = {7}, pages = {1029--1030} }
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Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exonsin Nature Communications, 5:4760, September 2014
@ARTICLE{Best2014, title = {Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons}, author = {Best, Andrew and James, Katherine and Dalgliesh, Caroline and Hong, Elaine and Kheirolahi-Kouhestani, Mahsa and Curk, Tomaz and Xu, Yaobo and Danilenko, Marina and Hussain, Rafiq and Keavney, Bernard and Wipat, Anil and Klinck, Roscoe and Cowell, Ian G. and Cheong Lee, Ka and Austin, Caroline A. and Venables, Julian P. and Chabot, Benoit and Santibanez Koref, Mauro and Tyson-Capper, Alison and Elliott, David J.}, year = 2014, doi = {10.1038/ncomms5760}, month = sep, journal = {Nature Communications}, volume = {5}, pages = {4760} }
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Conventional verification for unconventional computing: a genetic XOR gate examplein Fundamenta Informaticae, 134(1-2):97-110, November 2014
@ARTICLE{Konur2014, title = {Conventional verification for unconventional computing: a genetic XOR gate example}, author = {Konur, Savas and Gheorge, Marian and Dragomir, Ciprian and Ipate, Florin and Krasnogor, Natalio}, year = 2014, doi = {10.3233/FI-2014-1093}, month = nov, journal = {Fundamenta Informaticae}, volume = {134}, number = {1-2}, pages = {97--110} }
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A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Populationin PLoS ONE, 9(11):e111219, November 2014
@ARTICLE{Bauer2014a, title = {A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population}, author = {Bauer, Roman and Kaiser, Marcus and Stoll, Elizabeth}, year = 2014, doi = {10.1371/journal.pone.0111219}, month = nov, journal = {PLoS ONE}, volume = {9}, number = {11}, pages = {e111219} }
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Developmental Self-Construction and -Configuration of Functional Neocortical Neuronal Networksin PLoS Computational Biology, 10(12):e1003994, December 2014
@ARTICLE{Bauer2014b, title = {Developmental Self-Construction and -Configuration of Functional Neocortical Neuronal Networks}, author = {Bauer, Roman and Zubler, Frédéric and Pfister, Sabina and Hauri, Andreas and Pfeiffer, Michael and Muir, Dylan R. and Douglas, Rodney J.}, year = 2014, doi = {10.1371/journal.pcbi.1003994}, month = dec, journal = {PLoS Computational Biology}, volume = {10}, number = {12}, pages = {e1003994} }
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Parameter Synthesis for Cardiac Cell Hybrid Models Using δ-Decisionsin Computational Methods in Systems Biology, Lecture Notes in Computer Science 8859, p.99-113, 2014
@INCOLLECTION{Liu2014, title = {Parameter Synthesis for Cardiac Cell Hybrid Models Using δ-Decisions}, author = {Liu, Bing and Kong, Soonho and Gao, Sicun and Zuliani, Paolo and Clarke, Edmund M.}, year = 2014, doi = {10.1007/978-3-319-12982-2_8}, booktitle = {Computational Methods in Systems Biology}, publisher = {Springer International Publishing}, volume = {8859}, series = {Lecture Notes in Computer Science}, pages = {99--113} }
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Quasispecies in population of compositional assembliesin BMC Evolutionary Biology, 14(1):265, 2014
@ARTICLE{Gross2014, title = {Quasispecies in population of compositional assemblies}, author = {Gross, Renan and Fouxon, Itzhak and Lancet, Doron and Markovitch, Omer}, year = 2014, doi = {10.1186/s12862-014-0265-1}, journal = {BMC Evolutionary Biology}, volume = {14}, number = {1}, pages = {265} }
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BacillusRegNet: A transcriptional regulation database and analysis platform for Bacillus speciesin Journal of Integrative Bioinformatics, 11(2):244, 2014
@ARTICLE{Misirli2014, title = {BacillusRegNet: A transcriptional regulation database and analysis platform for Bacillus species}, author = {Misirli, G. and Hallinan, J. and Röttger, R. and Baumbach, J. and Wipat, A.}, year = 2014, url = {http://journal.imbio.de/article.php?aid=244}, journal = {Journal of Integrative Bioinformatics}, volume = {11}, number = {2}, pages = {244} }
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Infobiotics Workbench: A P Systems Based Tool for Systems and Synthetic Biologyin Applications of Membrane Computing in Systems and Synthetic Biology, Emergence, Complexity and Computation 7, p.1-41, 2014
@INCOLLECTION{Blakes2014a, title = {Infobiotics Workbench: A P Systems Based Tool for Systems and Synthetic Biology}, author = {Blakes, Jonathan and Twycross, Jamie and Konur, Savas and Romero-Campero, Francisco Jose and Krasnogor, Natalio and Gheorghe, Marian}, year = 2014, doi = {10.1007/978-3-319-03191-0_1}, booktitle = {Applications of Membrane Computing in Systems and Synthetic Biology}, publisher = {Springer International Publishing}, volume = {7}, series = {Emergence, Complexity and Computation}, pages = {1--41} }
2013
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Model Checking a Synchronous Diabetes-Cancer Logical Networkin Current Bioinformatics, 8(1):9-15, February 2013
@ARTICLE{Gong2013, title = {Model Checking a Synchronous Diabetes-Cancer Logical Network}, author = {Gong, Haijun and Zuliani, Paolo and M. Clarke, Edmund}, year = 2013, doi = {10.2174/157489313804871542}, month = feb, journal = {Current Bioinformatics}, volume = {8}, number = {1}, pages = {9--15} }
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Transcriptional Dynamics of Two Seed Compartments with Opposing Roles in Arabidopsis Seed Germinationin PLANT PHYSIOLOGY, 163(1):205-215, September 2013
@ARTICLE{Dekkers2013, title = {Transcriptional Dynamics of Two Seed Compartments with Opposing Roles in Arabidopsis Seed Germination}, author = {Dekkers, B. J. W. and Pearce, S. and van Bolderen-Veldkamp, R. P. and Marshall, A. and Widera, P. and Gilbert, J. and Drost, H. -g. and Bassel, G. W. and Muller, K. and King, J. R. and Wood, A. T. A. and Grosse, I. and Quint, M. and Krasnogor, N. and Leubner-Metzger, G. and Holdsworth, M. J. and Bentsink, L.}, year = 2013, doi = {10.1104/pp.113.223511}, month = sep, journal = {PLANT PHYSIOLOGY}, volume = {163}, number = {1}, pages = {205--215} }
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BacillOndex: An Integrated Data Resource for Systems and Synthetic Biologyin Journal of Integrative Bioinformatics, 10(2):224, 2013
@ARTICLE{Misirli2013, title = {BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology}, author = {Misirli, G. and Wipat, A. and Mullen, J. and James, K. and Pocock, M. and Smith, W. and Allenby, N. and Hallinan, J.}, year = 2013, doi = {10.2390/biecoll-jib-2013-224}, journal = {Journal of Integrative Bioinformatics}, volume = {10}, number = {2}, pages = {224} }
2012
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EnrichNet: network-based gene set enrichment analysisin Bioinformatics, 28(18):i451-i457, September 2012
@ARTICLE{Glaab2012a, title = {EnrichNet: network-based gene set enrichment analysis}, author = {Glaab, E. and Baudot, A. and Krasnogor, N. and Schneider, R. and Valencia, A.}, year = 2012, doi = {10.1093/bioinformatics/bts389}, month = sep, journal = {Bioinformatics}, volume = {28}, number = {18}, pages = {i451--i457} }
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Is There an Optimal Level of Open-Endedness in Prebiotic Evolution?in Origins of Life and Evolution of Biospheres, 42(5):469-474, October 2012
@ARTICLE{Markovitch2012, title = {Is There an Optimal Level of Open-Endedness in Prebiotic Evolution?}, author = {Markovitch, Omer and Sorek, Daniel and Lui, Leong Ting and Lancet, Doron and Krasnogor, Natalio}, year = 2012, doi = {10.1007/s11084-012-9309-y}, month = oct, journal = {Origins of Life and Evolution of Biospheres}, volume = {42}, number = {5}, pages = {469--474} }
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Computational Modeling and Verification of Signaling Pathways in Cancerin Algebraic and Numeric Biology, Lecture Notes in Computer Science 6479, p.117-135, 2012
@INCOLLECTION{Gong2012, title = {Computational Modeling and Verification of Signaling Pathways in Cancer}, author = {Gong, Haijun and Zuliani, Paolo and Komuravelli, Anvesh and Faeder, James R. and Clarke, Edmund M.}, year = 2012, doi = {10.1007/978-3-642-28067-2_7}, booktitle = {Algebraic and Numeric Biology}, publisher = {Springer Berlin Heidelberg}, volume = {6479}, series = {Lecture Notes in Computer Science}, pages = {117--135} }
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Is newer better?—evaluating the effects of data curation on integrated analyses in Saccharomyces cerevisiaein Integrative Biology, 4(7):715, 2012
@ARTICLE{James2012, title = {Is newer better?—evaluating the effects of data curation on integrated analyses in Saccharomyces cerevisiae}, author = {James, Katherine and Wipat, Anil and Hallinan, Jennifer}, year = 2012, doi = {10.1039/c2ib00123c}, journal = {Integrative Biology}, volume = {4}, number = {7}, pages = {715} }
2011
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SBML Level 3 Package Proposal: Annotationin Nature Precedings, available online since January 2011
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Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitionsin Proceedings of the National Academy of Sciences, 108(23):9709-9714, June 2011
@ARTICLE{Bassel2011a, title = {Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions}, author = {Bassel, G. W. and Lan, H. and Glaab, E. and Gibbs, D. J. and Gerjets, T. and Krasnogor, N. and Bonner, A. J. and Holdsworth, M. J. and Provart, N. J.}, year = 2011, doi = {10.1073/pnas.1100958108}, month = jun, journal = {Proceedings of the National Academy of Sciences}, volume = {108}, number = {23}, pages = {9709--9714} }
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RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtypein Breast Cancer Research and Treatment, 128(2):315-326, July 2011
@ARTICLE{Habashy2011, title = {RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype}, author = {Habashy, Hany Onsy and Powe, Desmond G. and Glaab, Enrico and Ball, Graham and Spiteri, Inmaculada and Krasnogor, Natalio and Garibaldi, Jonathan M. and Rakha, Emad A. and Green, Andrew R. and Caldas, C. and Ellis, Ian O.}, year = 2011, doi = {10.1007/s10549-010-1073-y}, month = jul, journal = {Breast Cancer Research and Treatment}, volume = {128}, number = {2}, pages = {315--326} }
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A thermodynamic switch modulates abscisic acid receptor sensitivityin The EMBO Journal, 30(20):4171-4184, October 2011
@ARTICLE{Dupeux2011, title = {A thermodynamic switch modulates abscisic acid receptor sensitivity}, author = {Dupeux, Florine and Santiago, Julia and Betz, Katja and Twycross, Jamie and Park, Sang-Youl and Rodriguez, Lesia and Gonzalez-Guzman, Miguel and Jensen, Malene Ringkjøbing and Krasnogor, Natalio and Blackledge, Martin and Holdsworth, Michael and Cutler, Sean R and Rodriguez, Pedro L and Márquez, José Antonio}, year = 2011, doi = {10.1038/emboj.2011.294}, month = oct, journal = {The EMBO Journal}, volume = {30}, number = {20}, pages = {4171--4184} }
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Formal analysis for logical models of pancreatic cancerin IEEE Conference on Decision and Control and European Control Conference, p.4855-4860, Orlando, FL, USA, December 2011
@INPROCEEDINGS{Gong2011, title = {Formal analysis for logical models of pancreatic cancer}, author = {Gong, Haijun and Zuliani, Paolo and Wang, Qinsi and Clarke, Edmund M.}, year = 2011, doi = {10.1109/CDC.2011.6161052}, month = dec, booktitle = {IEEE Conference on Decision and Control and European Control Conference}, pages = {4855--4860}, address = {Orlando, FL, USA} }
2010
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Evolving cell models for systems and synthetic biologyin Systems and Synthetic Biology, 4(1):55-84, March 2010
@ARTICLE{Cao2010, title = {Evolving cell models for systems and synthetic biology}, author = {Cao, Hongqing and Romero-Campero, Francisco J. and Heeb, Stephan and Cámara, Miguel and Krasnogor, Natalio}, year = 2010, doi = {10.1007/s11693-009-9050-7}, month = mar, journal = {Systems and Synthetic Biology}, volume = {4}, number = {1}, pages = {55--84} }
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TopoGSA: network topological gene set analysisin Bioinformatics, 26(9):1271-1272, May 2010
@ARTICLE{Glaab2010a, title = {TopoGSA: network topological gene set analysis}, author = {Glaab, E. and Baudot, A. and Krasnogor, N. and Valencia, A.}, year = 2010, doi = {10.1093/bioinformatics/btq131}, month = may, journal = {Bioinformatics}, volume = {26}, number = {9}, pages = {1271--1272} }
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Extending pathways and processes using molecular interaction networks to analyse cancer genome datain BMC Bioinformatics, 11(1):597, 2010
@ARTICLE{Glaab2010, title = {Extending pathways and processes using molecular interaction networks to analyse cancer genome data}, author = {Glaab, Enrico and Baudot, Anaïs and Krasnogor, Natalio and Valencia, Alfonso}, year = 2010, doi = {10.1186/1471-2105-11-597}, journal = {BMC Bioinformatics}, volume = {11}, number = {1}, pages = {597} }
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Analysis and verification of the HMGB1 signaling pathwayin BMC Bioinformatics, 11(Suppl 7):S10, 2010
@ARTICLE{Gong2010, title = {Analysis and verification of the HMGB1 signaling pathway}, author = {Gong, Haijun and Zuliani, Paolo and Komuravelli, Anvesh and Faeder, James R and Clarke, Edmund M}, year = 2010, doi = {10.1186/1471-2105-11-S7-S10}, journal = {BMC Bioinformatics}, volume = {11}, number = {Suppl 7}, pages = {S10} }
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P system model optimisation by means of evolutionary based search algorithmsin Proceedings of the 12th annual conference on Genetic and evolutionary computation - GECCO '10, p.187, Portland, Oregon, USA, 2010
@INPROCEEDINGS{Garcia-Martinez2010, title = {P system model optimisation by means of evolutionary based search algorithms}, author = {García-Martínez, Carlos and Lima, Claudio and Twycross, Jamie and Krasnogor, Natalio and Lozano, Manuel}, year = 2010, doi = {10.1145/1830483.1830517}, booktitle = {Proceedings of the 12th annual conference on Genetic and evolutionary computation - GECCO '10}, pages = {187}, address = {Portland, Oregon, USA} }
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Stochastic and deterministic multiscale models for systems biology: an auxin-transport case studyin BMC Systems Biology, 4(1):34, 2010
@ARTICLE{Twycross2010, title = {Stochastic and deterministic multiscale models for systems biology: an auxin-transport case study}, author = {Twycross, Jamie and Band, Leah R and Bennett, Malcolm J and King, John R and Krasnogor, Natalio}, year = 2010, doi = {10.1186/1752-0509-4-34}, journal = {BMC Systems Biology}, volume = {4}, number = {1}, pages = {34} }
2009
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Modular Assembly Of Cell Systems Biology Models Using P Systemsin International Journal of Foundations of Computer Science, 20(03):427-442, June 2009
@ARTICLE{Romero-Campero2009, title = {Modular Assembly Of Cell Systems Biology Models Using P Systems}, author = {Romero-Campero, Francisco J. and Twycross, Jamie and Cámara, Miguel and Bennett, Malcolm and Gheorghe, Marian and Krasnogor, Natalio}, year = 2009, doi = {10.1142/S0129054109006668}, month = jun, journal = {International Journal of Foundations of Computer Science}, volume = {20}, number = {03}, pages = {427--442} }
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A Multiscale Modeling Framework Based on P Systemsin Membrane Computing, Lecture Notes in Computer Science 5391, p.63-77, 2009
@INCOLLECTION{Romero-Campero2009a, title = {A Multiscale Modeling Framework Based on P Systems}, author = {Romero-Campero, Francisco José and Twycross, Jamie and Cao, Hongqing and Blakes, Jonathan and Krasnogor, Natalio}, year = 2009, doi = {10.1007/978-3-540-95885-7_5}, booktitle = {Membrane Computing}, publisher = {Springer Berlin Heidelberg}, volume = {5391}, series = {Lecture Notes in Computer Science}, pages = {63--77} }
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A Bayesian Approach to Model Checking Biological Systemsin Computational Methods in Systems Biology, Lecture Notes in Computer Science 5688, p.218-234, 2009
@INCOLLECTION{Jha2009, title = {A Bayesian Approach to Model Checking Biological Systems}, author = {Jha, Sumit K. and Clarke, Edmund M. and Langmead, Christopher J. and Legay, Axel and Platzer, André and Zuliani, Paolo}, year = 2009, doi = {10.1007/978-3-642-03845-7_15}, booktitle = {Computational Methods in Systems Biology}, publisher = {Springer Berlin Heidelberg}, volume = {5688}, series = {Lecture Notes in Computer Science}, pages = {218--234} }
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Integration of Full-Coverage Probabilistic Functional Networks with Relevance to Specific Biological Processesin Data Integration in the Life Sciences, Lecture Notes in Computer Science 5647, p.31-46, 2009
@INCOLLECTION{James2009, title = {Integration of Full-Coverage Probabilistic Functional Networks with Relevance to Specific Biological Processes}, author = {James, Katherine and Wipat, Anil and Hallinan, Jennifer}, year = 2009, doi = {10.1007/978-3-642-02879-3_4}, booktitle = {Data Integration in the Life Sciences}, publisher = {Springer Berlin Heidelberg}, volume = {5647}, series = {Lecture Notes in Computer Science}, pages = {31--46} }
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ArrayMining: a modular web-application for microarray analysis combining ensemble and consensus methods with cross-study normalizationin BMC Bioinformatics, 10(1):358, 2009
@ARTICLE{Glaab2009, title = {ArrayMining: a modular web-application for microarray analysis combining ensemble and consensus methods with cross-study normalization}, author = {Glaab, Enrico and Garibaldi, Jonathan M and Krasnogor, Natalio}, year = 2009, doi = {10.1186/1471-2105-10-358}, journal = {BMC Bioinformatics}, volume = {10}, number = {1}, pages = {358} }
2008
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Web and Grid Technologies in Bioinformatics, Computational and Systems Biology: A Reviewin Current Bioinformatics, 3(1):10-31, January 2008
@ARTICLE{Krasnogor2008b, title = {Web and Grid Technologies in Bioinformatics, Computational and Systems Biology: A Review}, author = {Krasnogor, Natalio and Shah, Azhar and Barthel, Daniel and Lukasiak, Piotr and Blazewicz, Jacek}, year = 2008, doi = {10.2174/157489308783329850}, month = jan, journal = {Current Bioinformatics}, volume = {3}, number = {1}, pages = {10--31} }
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Structure and parameter estimation for cell systems biology modelsin Proceedings of the 10th annual conference on Genetic and evolutionary computation - GECCO '08, p.331, Atlanta, GA, USA, 2008
@INPROCEEDINGS{Romero-Campero2008, title = {Structure and parameter estimation for cell systems biology models}, author = {Romero-Campero, Francisco J. and Cao, Hongqing and Camara, Miguel and Krasnogor, Natalio}, year = 2008, doi = {10.1145/1389095.1389153}, booktitle = {Proceedings of the 10th annual conference on Genetic and evolutionary computation - GECCO '08}, pages = {331}, address = {Atlanta, GA, USA} }
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A multi-scaled approach to artificial life simulation with P systems and dissipative particle dynamicsin Proceedings of the 10th annual conference on Genetic and evolutionary computation - GECCO '08, p.249, Atlanta, GA, USA, 2008
@INPROCEEDINGS{Smaldon2008, title = {A multi-scaled approach to artificial life simulation with P systems and dissipative particle dynamics}, author = {Smaldon, James and Blakes, Jonathan and Krasnogor, Natalio and Lancet, Doron}, year = 2008, doi = {10.1145/1389095.1389134}, booktitle = {Proceedings of the 10th annual conference on Genetic and evolutionary computation - GECCO '08}, pages = {249}, address = {Atlanta, GA, USA} }
2007
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Quorum sensing P systemsin Theoretical Computer Science, 371(1-2):20-33, February 2007
@ARTICLE{Bernardini2007, title = {Quorum sensing P systems}, author = {Bernardini, Francesco and Gheorghe, Marian and Krasnogor, Natalio}, year = 2007, doi = {10.1016/j.tcs.2006.10.012}, month = feb, journal = {Theoretical Computer Science}, volume = {371}, number = {1-2}, pages = {20--33} }
2006
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On P Systems as a Modelling Tool for Biological Systemsin Membrane Computing, Lecture Notes in Computer Science 3850, p.114-133, 2006
@INCOLLECTION{Bernardini2006, title = {On P Systems as a Modelling Tool for Biological Systems}, author = {Bernardini, Francesco and Gheorghe, Marian and Krasnogor, Natalio and Muniyandi, Ravie C. and Pérez-Jímenez, Mario J. and Romero-Campero, Francisco José}, year = 2006, doi = {10.1007/11603047_8}, booktitle = {Membrane Computing}, publisher = {Springer Berlin Heidelberg}, volume = {3850}, series = {Lecture Notes in Computer Science}, pages = {114--133} }
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Towards a P Systems Pseudomonas Quorum Sensing Modelin Membrane Computing, Lecture Notes in Computer Science 4361, p.197-214, 2006
@INCOLLECTION{Bianco2006, title = {Towards a P Systems Pseudomonas Quorum Sensing Model}, author = {Bianco, Luca and Pescini, Dario and Siepmann, Peter and Krasnogor, Natalio and Romero-Campero, Francisco J. and Gheorghe, Marian}, year = 2006, doi = {10.1007/11963516_13}, booktitle = {Membrane Computing}, publisher = {Springer Berlin Heidelberg}, volume = {4361}, series = {Lecture Notes in Computer Science}, pages = {197--214} }
2005
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An Environment Aware P-System Model of Quorum Sensingin New Computational Paradigms, Lecture Notes in Computer Science 3526, p.479-485, 2005
@INCOLLECTION{Terrazas2005, title = {An Environment Aware P-System Model of Quorum Sensing}, author = {Terrazas, German and Krasnogor, Natalio and Gheorghe, Marian and Bernardini, Francesco and Diggle, Steve and Cámara, Miguel}, year = 2005, doi = {10.1007/11494645_59}, booktitle = {New Computational Paradigms}, publisher = {Springer Berlin Heidelberg}, volume = {3526}, series = {Lecture Notes in Computer Science}, pages = {479--485} }