Scalp EEG normative brain mapping and its clinical applications

Comparing patients with normalised healthy controls to expose pathology is common in neuroimaging and is gaining traction in neurophysiology. In recent studies, data from magnetoencephalography (MEG) and intracranial electroencephalography (EEG) have been used successfully to identify abnormalities using normative mapping. As these methods are expensive or highly invasive, scalp EEG has been reconsidered as an alternative, but normative mapping is not yet used routinely with it.

In this talk, I will present the scalp EEG normative map and discuss band power variation across regions and time. Then, I will show correlations of scalp EEG to intracranial and MEG normative maps. Finally, I will briefly introduce potential application of scalp EEG normative mapping to locate abnormal brain regions for an individual patient.