On computer simulations of brain development

Based on the vast improvements of computing power in the last few years, it has become possible to conduct neuroscientific research using highly detailed models. These models often incorporate biologically plausible morphology and electrical activity patterns. However, one crucial aspect that has been neglected in many computational studies of the brain is development. Our brains are the result of a well-orchestrated developmental process that starts from a single precursor cell, the zygote.

In this talk I will argue that improving our understanding of neural development is key in understanding neural structure, function and many brain diseases. I will comment on implications of such developmental models, also with respect to synthetic biology and computer science. Along these lines, I will present some of my work , and describe current challenges and plans for the near future.