Microfluidic techniques for single cell analysis

Synthetic biology aims to develop organisms with novel functionality. While computational designs are an essential part in the synthetic biology, there still exists a disconnect between the designs achievable in silico and in vivo. Such a discrepancy arises, in part, from the limitation in the computation designs having to deal with calculations on a single-cell basis, whereas in the in vivo counterpart, measurements are taken on populations of cells. Single-cell based in vivo analysis techniques can close this gap. Single-cell based microfluidic techniques are introduced, which can provide finer control into measuring cellular dynamics that are more prone to cancelling out in population based measurements.